Adequan Multi Dose

First, Adequan has important anti-inflammatory effects, so it is able to provide relief from the symptoms of joint damage: heat, swelling, pain and lameness. And Adequan can be found in synovial fluid at full herapeutic levels within only two hours of an intramuscular injection. Also, Adequan is a product with potent ability to block the action of the destructive enzymes that threaten to perpetuate the joint inflammation, attack the cartilage and break down synovial fluid.

Second, Adequan stimulates the synovial membrane to manufacture new, viscous synovial fluid to replace the thin fluid that was produced when the joint became injured. By improving this fluid, Adequan helps the joint regain its ability to lubricate and guard itself against further inflammation, and helps reestablish nutrition to the cartilage. And, Adequan attaches itself to damaged cartilage where it has a positive effect on cartilage metabolism. This should favor the cartilage repair process.

Adequan is the only joint treatment proven to reduce the inflammation and pain of degenerative joint disease, but also to help stop the degenerative process while stimulating the production of new joint fluid and new cartilage components. You are no longer just treating symptoms: you’re doing something to help stop the degenerative process.

Indications

Adequan i.m. is recommended for the intramuscular treatment of non-infectious degenerative and/or traumatic joint dysfunction and associated lameness of the carpal and hock joints in horses.

Key Benefits

• The only joint treamtent with proven results
• Fast results within hours
• Easy-to-use with injection

Active Ingredient

Polysulfated Glycosaminoglycan (PSGAG), 100 mg / mL

View Adequan i.m. package label.

Dosage and Administration

Practice aseptic techniques in withdrawing each dose to decrease the possibility of post-injection bacterial infections. Adequately clean and disinfect the stopper prior to entry with a sterile needle and syringe. Use only sterile needles, and use each needly only once.

The vial stopper may be punctured a maximum of 10 times.

The recommended dose of Adequan i.m. Multi-Dose in horses is 500 mg every 4 days for 28 days intramuscularly. The injection site must be thoroughly cleansed prior to injection. Do not mix Adequan i.m. Multi-Dose with other drugs or solvents.

Contraindications

There are no known contraindications to the use of intramuscular Polysulfated Glycosaminoglycan.

Warnings

Do not use in horses intended for human consumption. Not for use in humans. Keep this and all medications out of the reach of children.

Precautions

The safe use of Adequan i.m. in horses used for breeding purposes, during pregnancy, or in lactating mares has not been evaluated.

Animal Safety

Toxicity studies were conducted in horses. Doses as high as 2,500 mg were administered intramuscularly to 6 horses twice a week for 12 weeks. This dosage is 5 times the recommended dosage and 3 times the recommended therapeutic regimen. Clinical observations revealed no soreness or swelling at the injection site or in the affected joint. No animal had any clinical or laboratory evidence of toxicity.

Storage

Store and 20°-25°C (68°-77°F); excursions permitted to 15°-30°C (59°-86°F). Keep out of reach of children and animals. Avoid prolonged exposure to temperature greater than 40°C (104°F).

Use within 28 days of first puncture and puncture a maximum of 10 times. Dispose of spent needles in accordance with all federal, state, and local environmental laws.